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AKT serine/threonine kinase 2

SKU BW-MB62166-25ul
Original price $376.55 - Original price $892.07
Original price
$376.55
$376.55 - $892.07
Current price $376.55

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

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