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ARL2BP polyclonal antibody detects endogenous levels of ARL2BP protein.

SKU BW-BS61595-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14
$354.14 - $616.38
Current price $354.14

ADP-ribosylation factors (ARFs) are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL2 (ADP-ribosylation factor-like protein 2) functions as a component of a secretory pathway that is involved in the calcium-dependent release of acetylcholine. Additionally, ARL2 plays a role in the folding of tubule proteins, thereby playing an important role in microtubule dynamics and cell cycle progression. BART1 (Binder of ARL2 protein 1), also known as ARL2BP (ADP-ribosylation factor-like protein 2-binding protein), is a 163 amino acid protein that interacts with GTP-bound ARL2 complexes and therefore may play a role in modulating ARL2 activity. Though predominantly cytosolic, BART1 can enter the mitochondria and bind the adenine nucleotide transporter when bound to ARL2. There are two isoforms of BART1 that are produced as a result of alternative splicing events.

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