ATIC polyclonal antibody detects endogenous levels of ATICprotein.
by Bioworld
SKU BW-BS6973-50ul
Original price
$466.21
-
Original price
$802.41
Original price
$466.21
$466.21
-
$802.41
Current price
$466.21
The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic.
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