BcMag™ TR-FRET Assay is a time-resolved fluorescence resonance energy transfer assay that uses time-resolved fluorescence magnetic beads as the donor fluorophore. It allows for the detection of trace amounts of analytes in a sample, resulting in higher sensitivity, and eliminates background fluorescence caused by the sample and plastic microplate. This assay offers advantages in high throughput screening, such as assay flexibility, dependability, increased assay sensitivity, higher throughput, and fewer false positive/false negative results. It does not require washing steps.