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Adducin ? (P452) polyclonal antibody detects endogenous levels of Adducin ? protein.

SKU BW-BS2209-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14 - $616.38
Current price $354.14

Adducins are a family of cytoskeleton proteins encoded by three genes (?, ? and ?). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and adducins are central in the cortical actin network organization. Adducin ? is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin ? and Adducin ? is ubiquitous in contrast to the restricted expression of Adducin ?. Adducin ? is expressed at high levels in brain andhematopoietic tissues, such as bone marrow in humans, and spleen in mice.

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