ARMC6 polyclonal antibody detects endogenous levels of ARMC6 protein.
The armadillo (ARM) repeat family of proteins are related to the Drosophila
melanogaster armadillo protein, a protein essential for wingless signal transduction.
ARM proteins are involved in a variety of processes such as cell
migration, cell proliferation, tissue maintenance and tumorigenesis. They are
intracellular proteins that function in signal transduction and cell structure.
ARMC6 (armadillo repeat-containing protein 6) is a 501 amino acid protein
that contains four ARM domains. The gene encoding ARMC6 maps to chromosome
19p13.11. Chromosome 19 is recognized for having the greatest gene
density of the human chromosomes. It is the genetic home for a number of
immunoglobulin superfamily members, including the killer cell and leukocyte
Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc
receptors.
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