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C/EBP-? (K70) polyclonal antibody detects endogenous levels of C/EBP-? protein.

SKU BW-BS1516-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14 - $616.38
Current price $354.14

C/EBP ? regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP ? uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic ? helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP ? appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C/EBP ?, C/EBP ?, C/EBP ? and C/EBP ?, all of which exhibit similar DNA-binding specificities and affinities to C/EBP ?. Furthermore, C/EBP ? and C/EBP ? readily form heterodimers both with each other as well as with C/EBP ?.

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