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CASP7 polyclonal antibody detects endogenous levels of CASP7 protein.

SKU BW-BS3532-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14
$354.14 - $616.38
Current price $354.14

Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis (1-4). Caspase-7, like caspase-3, is an effector caspase that is responsible for cleaving downstream substrates such as (ADP-ribose) polymerase and PARP . During apoptosis, caspase-7 is activated through proteolytic processing by upstream caspases at Asp23, Asp198, and Asp206 to produce the mature subunits . Similar to caspase-2 and -3, caspase-7 preferentially cleaves substrates following the recognition sequence DEVD .

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Overnight if in stock

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