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CHOP (K121) polyclonal antibody detects endogenous levels of CHOP protein.

SKU BW-BS1136-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14 - $616.38
Current price $354.14

GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.

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Overnight if in stock

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