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Cyclin D1 polyclonal antibody detects endogenous levels of Cyclin D1 protein.

SKU BW-BS6532-50ul
Original price $466.21 - Original price $802.41
Original price
$466.21 - $802.41
Current price $466.21

Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors.

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