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GABAA R?1 (R328) polyclonal antibody detects endogenous levels of GABAA R?1 protein.

SKU BW-BS1134-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14
$354.14 - $616.38
Current price $354.14

GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R?1-6, GABAA R ?1-3, GABAA R?1-3, GABAA R?, GABAA R?, GABAA R?1 and GABAA R?2. The GABAB family is composed of GABAB R1? and GABAB R1?. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

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Overnight if in stock

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