{"product_id":"il-1-af-cgs-gfh173af-500","title":"IL-1 α (AF)","description":"\u003cp\u003eInterleukin-1 α (IL-1 α) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL-1 ? signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll\/IL-1 receptor (TIR) domain adapter. IL-1 ? and the independently regulated IL-1 ? protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.\u003c\/p\u003e","brand":"Cell Guidance Systems","offers":[{"title":"500 μg","offer_id":49299558990080,"sku":"CGS-GFH173AF-500","price":5793.15,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0663\/6591\/5392\/files\/GFH173_1_3a1f754b-1fc9-4f38-8094-6c82bfed7d4a.jpg?v=1787287740","url":"https:\/\/shop.customscience.co.nz\/products\/il-1-af-cgs-gfh173af-500","provider":"Custom Science Ltd","version":"1.0","type":"link"}