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IL-15

SKU CGS-GFH86-10
Original price $442.11 - Original price $10,539.30
Original price
$442.11
$442.11 - $10,539.30
Current price $442.11
Interleukin-15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin-2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. IL-15 regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function. IL-15 expression is dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases. Human IL-15 shows activity on mouse cells.

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