{"product_id":"il-17a-af-cgs-gfm59af-500","title":"IL-17A (AF)","description":"\u003cp\u003eInterleukin-17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites. Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.\u003c\/p\u003e","brand":"Cell Guidance Systems","offers":[{"title":"500 μg","offer_id":49299776864512,"sku":"CGS-GFM59AF-500","price":4462.2,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0663\/6591\/5392\/files\/GFM59_1_d6628c37-c451-40d7-814e-aba391a41b98.jpg?v=1787287886","url":"https:\/\/shop.customscience.co.nz\/products\/il-17a-af-cgs-gfm59af-500","provider":"Custom Science Ltd","version":"1.0","type":"link"}