{"product_id":"il-21-af-cgs-gfh90af-1000","title":"IL-21 (AF)","description":"\u003cp\u003eInterleukin-21 (IL-21) is a member of the common-? chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells and is aberrantly expressed in Hodgkin lymphoma cells. The IL-21 receptor (IL-21R) activates the JAK\/STAT signaling pathway and is expressed on T, B, and Natural Killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with IL-4 for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.\u003c\/p\u003e","brand":"Cell Guidance Systems","offers":[{"title":"1 mg","offer_id":49300113391872,"sku":"CGS-GFH90AF-1000","price":13234.46,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0663\/6591\/5392\/files\/GFH90_1_ce807523-2c89-4c14-8278-34f46a6fcdd7.jpg?v=1787288117","url":"https:\/\/shop.customscience.co.nz\/products\/il-21-af-cgs-gfh90af-1000","provider":"Custom Science Ltd","version":"1.0","type":"link"}