The Mag-Bind Total RNA Kit provides a novel technology for total RNA isolation. This kit allows the rapid and reliable isolation of high-quality total cellular RNA from a wide variety of cells and tissues. The system combines the higher nucleic acid-binding properties of Mag-Bind Particles with the E.Z.N.A. RNA Isolation system to provide superior quality of RNA. Unlike column-based systems, the binding of nucleic acids to magnetic particles occurs in solution, resulting in increased binding kinetics and binding efficiency. Particles are also completely re-suspended during the wash steps of the purification protocol, which enhances contact with the wash buffer and removal of contaminants and increasing nucleic acid purity. E.Z.N.A. Mag-Bind Total RNA procedure can be fully automated with most robotic workstations.