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MMP-11 (G88) polyclonal antibody detects endogenous levels of MMP-11 protein.

SKU BW-BS1230-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14
$354.14 - $616.38
Current price $354.14

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or taphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin- 1, -2 and -3) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and it is expressed at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

Delivery time

Overnight if in stock

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Purchase orders from approved customers and Credit Cards are accepted as forms of payment

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