Skip to content
Free Shipping when you spend NZ$500+
Free Shipping when you spend NZ$500+

NRDP1 polyclonal antibody detects endogenous levels of NRDP1 protein.

SKU BW-AP6041-50ul
Original price $466.21 - Original price $802.41
Original price
$466.21
$466.21 - $802.41
Current price $466.21

The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03 or FLRF, is a 317 amino acid protein that contains one RING-type zinc finger and one SIAH-type zinc finger. Expressed in testis, ovary and prostate, Nrdp1 functions as an E3 ubiquitin-protein ligase that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, Nrdp1 interacts with ErbB-3 and UBPY, thereby targeting them for proteasomal degradation.

Delivery time

Overnight if in stock

Payment Methods

Purchase orders from approved customers and Credit Cards are accepted as forms of payment

Compare products

{"one"=>"Select 2 or 3 items to compare", "other"=>"{{ count }} of 3 items selected"}

Select first item to compare

Select second item to compare

Select third item to compare

Compare