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p-AR (S650) polyclonal antibody detects endogenous levels of Androgen Receptor protein only when phosphorylated at Ser650 .

SKU BW-BS4012-50ul
Original price $376.55 - Original price $667.93
Original price
$376.55
$376.55 - $667.93
Current price $376.55

Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.

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