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p-Caspase-9 (T125) polyclonal antibody detects endogenous levels of Caspase-9 protein only when phosphorylated at Thr125.

p-Caspase-9 (T125) polyclonal antibody detects endogenous levels of Caspase-9 protein only when phosphorylated at Thr125.

by Bioworld
SKU BW-BS4221-50ul
$376.55 - $667.93
$376.55
$376.55 - $667.93
$376.55

Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6.

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