p-Eg5 (T926) pAb detects endogenous levels of Eg5 protein only when phosphorylated at Thr926.
Eg5 (also called kinesin-like protein 11 or Kif11) belongs to the kinesin-like family of motor proteins important in chromosome positioning, centrosome separation, and mitotic spindle formation. Phosphorylation of Eg5 by mitotic kinases regulates its activity by modulating its association with microtubules. Because anti-mitotic chemotherapeutic drugs, such as taxanes, target microtubules and have pleiotropic and sometimes toxic effects, drugs that target microtubule-associated proteins such as Eg5 are currently in development.
Delivery time
Overnight if in stock
Payment Methods
Purchase orders from approved customers and Credit Cards are accepted as forms of payment