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p-p130 Cas (Y410) polyclonal antibody detects endogenous levels of p130 Cas protein only when phosphorylated at Tyr410.

p-p130 Cas (Y410) polyclonal antibody detects endogenous levels of p130 Cas protein only when phosphorylated at Tyr410.

by Bioworld
SKU BW-BS4244-50ul
$376.55 - $667.93
$376.55
$376.55 - $667.93
$376.55

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.

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