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PKC beta (Phospho-S661) polyclonal antibody detects endogenous levels of PKC beta protein only when phosphorylated at Ser661.

SKU BW-BS64559-50ul
Original price $466.21 - Original price $802.41
Original price
$466.21
$466.21 - $802.41
Current price $466.21

PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (?, ?I, ?II and ?) and novel (n) PKC isoforms (?, ?, ?, ? and ?). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC ? and ? are independent of Ca2+. On the other hand, nPKC ? and ?, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.

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Overnight if in stock

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