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PSAT1 polyclonal antibody detects endogenous levels of PSAT1 protein.

SKU BW-BS8371-50ul
Original price $466.21 - Original price $802.41
Original price
$466.21
$466.21 - $802.41
Current price $466.21

PSAT1 (phosphoserine aminotransferase 1), also known as phosphoserine aminotransferase, phosphohydroxythreonine aminotransferase, endometrial progesterone-induced protein, PSA, PSAT, EPIP or MGC1460, is a 370 amino acid protein belonging to the class-V pyridoxal-phosphate-dependent aminotransferase family and serC subfamily. PSAT1 catalyzes the second step in the L-serine synthesis pathway, converting 3-phosphohydroxypyruvate into 3-phosphoserine. While highly expressed in pancreas, brain, kidney and liver, PSAT1 is expressed at very low levels in colon, testis, thymus and prostate. There are two known isoforms of PSAT1 which result from alternative splicing events, and the gene encoding PSAT1 maps to human chromsome 9q21.2. PSAT1 deficiency can cause phosphoserine aminotransferase deficiency (PSATD), whose symptoms include psychomotor retardation, intractable seizures, acquired microcephaly and hypertonia.

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