Recognizes endogenous levels of AAK1 protein.
by Bioworld
SKU BW-BS67123-50ul
Original price
$354.14
-
Original price
$616.38
Original price
$354.14
$354.14
-
$616.38
Current price
$354.14
Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis (PubMed:17494869, PubMed:11877457, PubMed:11877461, PubMed:12952931, PubMed:14617351, PubMed:25653444).Isoform 1 and isoform 2 display similar levels of kinase activity towards AP2M1 (PubMed:17494869).
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