The 14-3-3 proteins are a highly conserved family of proteins involved in the regulation of cell survival, apoptosis, proliferation and checkpoint control . Biological regulation by 14-3-3 is mediated through phosphorylation-dependent protein-protein interactions . Two different phospho-Ser-containing motifs are found within nearly all known 14-3-3 binding proteins . Motif is found in critical regulatory proteins including Bad, cdc25C, FKHRL1, PKC and c-Raf . Phospho-14-3-3 Binding Motif Polyclonal and Monoclonal Antibodies provide powerful tools for the discovery and characterization of potential 14-3-3 binding proteins containing this motif and for high throughput drug discovery.