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Recognizes endogenous levels of Cytochrome P450 1A2 protein.

SKU BW-MB66805-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14
$354.14 - $616.38
Current price $354.14

CYP1A2, also called cytochrome P450 1A2, is a heme-thiolate monooxygenase enzyme involved in the NADPH-dependent electron transport pathway of liver microsomes. A member of the cytochrome P450 family, CYP1A2 oxidizes fatty acids, steroids and xenobiotics. It is also involved in the metabolism of imiprimine, propranol and clozapine. CYP1A2 localizes to the membrane of the endoplasmic reticulum. It is induced by 3-methylcholanthrene, Insulin, modafinil and hyperforin and inhibited by many fluoroquinolone antibiotics, caffeine, fluvoxamine and cimetidine. In addition, the involvement of CYP1A2 in the metabolism of estrogen is associated with a reduced risk of breast cancer.

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