Recognizes endogenous levels of GAP43 protein.
by Bioworld
SKU BW-BS67791-50ul
Original price
$354.14
-
Original price
$616.38
Original price
$354.14
$354.14
-
$616.38
Current price
$354.14
GAP43 is a nervous system specific, growth-associated protein enriched in growth cones and areas of high plasticity. Phosphorylation of GAP43 at Ser41 by PKC is regulated by intracellular Ca2+ and affects the ability of GAP43 to bind calmodulin. GAP43 is integral to growth cone formation, neurite outgrowth, and the development of a functional cerebral cortex. Aberrant GAP43 expression can be seen in patients diagnosed with schizophrenia and Alzheimer's disease.
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