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Recognizes endogenous levels of Histone H2B with an acetylation site at K120 protein.

SKU BW-BS67561-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14
$354.14 - $616.38
Current price $354.14

Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones ore component of nucleosome .Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability .DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling .Also found in fat cells, its function and the presence of post-translational modifications specific to such cells are still unclear.

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