Recognizes endogenous levels of MKK2 protein.
by Bioworld
SKU BW-MB65962-50ul
Original price
$354.14
-
Original price
$616.38
Original price
$354.14
$354.14
-
$616.38
Current price
$354.14
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
Activates BRAF in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (PubMed:29433126).
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