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Recognizes endogenous levels of OCT1 with a phosphorylation site at S385 protein.

SKU BW-BS67588-50ul
Original price $376.55 - Original price $667.93
Original price
$376.55
$376.55 - $667.93
Current price $376.55

Oct-1 (POU2F1) is a ubiquitously expressed, octamer-binding transcription factor containing a POU domain with a homeobox subdomain . Oct-1 has been shown to interact with several transcription factors in mediating specific gene expression, including SNAPc , OBF-1 (a B-cell transcriptional coactivator protein) , TFIIB , and TBP (TATA-box-binding protein) . Its POU DNA-binding domain allows Oct-1 the flexibility to facilitate the binding and recruitment of several tissue-specific cofactors to either positively or negatively regulate a variety of genes, exerting an important role in development.

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