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Recognizes endogenous levels of Parvalbumin alpha protein.

SKU BW-BS67762-50ul
Original price $354.14 - Original price $616.38
Original price
$354.14
$354.14 - $616.38
Current price $354.14

Parvalbumin (PV, PVALB) is a member of the EF-hand family of calcium-binding proteins, containing EF-hand domains with a high affinity for calcium and magnesium. Parvalbumin is expressed in both the soma and in processes of specific subclasses of GABAergic interneurons. Parvalbumin is a slow calcium buffer, meaning it accelerates the initial phase of decay of calcium after an action potential, which likely inhibits facilitation and is thought to regulate short-term synaptic plasticity. Altered function of PV positive interneurons has been implicated in many neurological diseases, such as Alzheimer’s disease, autism spectrum disorder, schizophrenia, and bipolar disorder.

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