Recognizes endogenous levels of PP1 alpha protein.
by Bioworld
SKU BW-MB66507-50ul
Original price
$354.14
-
Original price
$616.38
Original price
$354.14
$354.14
-
$616.38
Current price
$354.14
Type 1 protein phosphatase (PP1), a serine/threonine phosphatase, is highly conserved in eukaryotic cells. Four isoforms of PP1 have been characterized: PP1?, PP1?, PP1?1 and PP1?2 . Involvement in cell cycle regulation is one of the biological functions of PP1 . It has been illustrated that PP1 dephosphorylates Rb and cdc25 during mitosis . A cell cycle-dependent phosphorylation at Thr320 of PP1? by cdc2 kinase inhibits PP1? activity.
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