Recognizes endogenous levels of WASP (pY290) protein.
Effector protein for Rho-type GTPases that regulates actin filament reorganization via its interaction with the Arp2/3 complex (PubMed:12235133, PubMed:12769847, PubMed:16275905).Important for efficient actin polymerization (PubMed:8625410, PubMed:12235133, PubMed:16275905).Possible regulator of lymphocyte and platelet function (PubMed:9405671).
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