
RET (Phospho-Y981) polyclonal antibody detects endogenous levels of RET protein only when phosphorylated at Tyr981.
The Ret gene products include two glycosylated proteins and, in tunicamycin treated cells, a non-glycosylated protein consistent with the predicted Ret molecular weight based on sequence analysis. Tumor-specific rearrangements of the Ret proto-oncogene have been identified in papillary thyroid carcinomas leading to the formation of different transforming fusion proteins sharing the tyrosine kinase domain of Ret. In contrast to the Ret proto-oncogene, the rearranged forms are constitutively phosphorylated on tyrosine and are translocated from the membrane to the cytoplasm.
Delivery time
Overnight if in stock
Payment Methods
Purchase orders from approved customers and Credit Cards are accepted as forms of payment