RGD peptide is a synthetic peptide containing the RGD cell attachment sequence found in fibronectin, vitronectin and many other matrix and serum proteins. The binding of this peptide is mediated via a hydroscopic C-terminal sequence fused to the RGD motif, providing a multi-modal mechanism of action which optimizes cell attachment and activation via integrin receptors. This RGD peptide has been specifically engineered to spontaneously adhere to various surfaces such as polystyrene (either tissue culture treated or non-treated), hollow fibres made of cellulose, glass, polycarbonate membranes and many other materials. This enables enhanced use in a wide range of cell culture applications.