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SMARCAD1 polyclonal antibody detects endogenous levels of SMARCAD1 protein.

SKU BW-BS7898-50ul
Original price $466.21 - Original price $802.41
Original price
$466.21 - $802.41
Current price $466.21

Smarcad1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1), also known as ETL1 or HEL1, is a 1,026 amino acid nuclear protein suggested to function as an ATPdependent DNA helicase. A member of the SNF2/RAD54 helicase family, Smarcad1 undergoes post-translational phosphorylation by either ATM or ATR and contains one helicase C-terminal domain, a helicase ATP-binding domain and two CUE domains. Existing as two alternatively spliced isoforms, Smarcad1 is encoded by a gene that maps to human chromosome 4, which represents approximately 6% of the human genome, contains nearly 900 genes and is associated with Huntington’s disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

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