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TAF1C polyclonal antibody detects endogenous levels of TAF1C protein.

SKU BW-BS8417-50ul

For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter- and RNA polymerase-specific complexes.

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Overnight if in stock

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