TPD52 polyclonal antibody detects endogenous levels of TPD52 protein.
by Bioworld
SKU BW-BS71498-50ul
The tumor protein D52 (TPD52) family consists of three members, TPD52, TPD52L1 (D53) and TPD52L2 (D54). These small coiled-coil motif bearing proteins interact in hetero- and homomeric fashion. The TPD52 gene maps to chromosome 8q21.13 and due to amplification, shows frequent overexpression in prostate and breast carcinomas. TPD52 binds to annexin VI in a Ca2+-dependent manner, suggesting that these molecules may act in concert to regulate secretory processes in plasma cells.
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