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Vascular Endothelial Growth Factor 120 (VEGF-120) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-120 is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. Mouse VEGF-A has several alternatively spliced isoforms, with one being VEGF-120. VEGF-120 is an angiogenic factor that is expressed throughout endochondral bone development and is important during skeletogenesis.

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