U0126
SKU CGS-SM106-5
Original price
$126.32
-
Original price
$1,955.79
Original price
$126.32
$126.32
-
$1,955.79
Current price
$126.32
U0126 is a selective MAP Kinase inhibitor, displaying a preference for MEK-1 and MEK-2. It is known that U0126 binds to MEK in a noncompetitive manner compared to ATP. Studies suggest that U0126 antagonizes the transcription of AP-1, via the inhibition of MEK. In addition, U0126 has been observed to inhibit promoters containing an AP-1 response element, while in contrast having no effect on promoters that lack an AP-1 response group. U0126 is an activator of PGC-1, mtTFA and Nuclear Respiratory Factor.
Delivery time
Overnight if in stock
Payment Methods
Purchase orders from approved customers and Credit Cards are accepted as forms of payment